Robust neuronal differentiation of human iPSC-derived neural progenitor cells cultured on densely-spaced spiky silicon nanowire arrays

Abstract Nanostructured cell culture substrates featuring nanowire (NW) arrays have been applied to a variety of basic cell lines and rodent neurons to investigate cellular behavior or to stimulate cell responses. However, patient-derived human neurons—a prerequisite for studying e.g. neurodegenerat...

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Bibliographic Details
Main Authors: Jann Harberts, Malte Siegmund, Matteo Schnelle, Ting Zhang, Yakui Lei, Linwei Yu, Robert Zierold, Robert H. Blick
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-97820-4