Imaging of mitochondrial and non-mitochondrial responses in cultured rat hippocampal neurons exposed to micromolar concentrations of TMRM.

Imaging of mitochondrial and non-mitochondrial responses in cultured rat hippocampal neurons exposed to micromolar concentrations of TMRM.

Tetramethylrhodamine methyl ester (TMRM) is a fluorescent dye used to study mitochondrial function in living cells. Previously, we reported that TMRM effectively labeled mitochondria of neurons deep within mouse brain slices. Use of micromolar concentration of dye, which was required to get sufficie...

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Bibliographic Details
Main Authors: Andrew Monteith, William Marszalec, Philip Chan, Juliette Logan, Weiming Yu, Nicholas Schwarz, David Wokosin, Philip Hockberger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3587568?pdf=render

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http://europepmc.org/articles/PMC3587568?pdf=render

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