Influence of intramolecular hydrogen bonds on the binding potential of methylated β-cyclodextrin derivatives

Various heptasubstituted derivatives of β-cyclodextrin (β-CD) bearing 1, 2 and 3 methyl substituents per glucose unit were synthesized by regioselective methods. Binding free energies and binding enthalpies of these hosts towards 4-tert-butylbenzoate and adamantane-1-carboxylate were determined by i...

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Bibliographic Details
Main Author: Gerhard Wenz
Format: Article
Language:English
Published: Beilstein-Institut 2012-11-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.8.218