Impact of HCMV infection on NK cell development and function after HSCT

Impact of HCMV infection on NK cell development and function after HSCT

Natural Killer (NK) cell function is regulated by an array of inhibitory and activating surface receptors that during NK cell differentiation, at variance with T and B cells, do not require genetic rearrangement. Importantly, NK cells are the first lymphocyte population recovering after hematopoieti...

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Bibliographic Details
Main Authors: Mariella eDella Chiesa, Michela eFalco, Letizia eMuccio, Alice eBertaina, Franco eLocatelli, Alessandro eMoretta
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Immunology
Subjects:
Hematopoietic Stem Cell Transplantation
KIR
human NK cells
HCMV infection
NKG2C
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00458/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00458/full

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