The Clostridium difficile Protease Cwp84 Modulates both Biofilm Formation and Cell-Surface Properties.

The Clostridium difficile Protease Cwp84 Modulates both Biofilm Formation and Cell-Surface Properties.

Clostridium difficile is responsible for 15-20% of antibiotic-associated diarrheas, and nearly all cases of pseudomembranous colitis. Among the cell wall proteins involved in the colonization process, Cwp84 is a protease that cleaves the S-layer protein SlpA into two subunits. A cwp84 mutant was pre...

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Bibliographic Details
Main Authors: Véronique Pantaléon, Anna Philibertine Soavelomandroso, Sylvie Bouttier, Romain Briandet, Bryan Roxas, Michele Chu, Anne Collignon, Claire Janoir, Gayatri Vedantam, Thomas Candela
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4414356?pdf=render

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http://europepmc.org/articles/PMC4414356?pdf=render

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