pH and Redox Dual-Sensitive Covalent Organic Framework Nanocarriers to Resolve the Dilemma Between Extracellular Drug Loading and Intracellular Drug Release

Cancer poses a serious threat to human health. To enhance the efficacy of tumor chemotherapy, it is urgent to develop novel and effective nanocarriers with the ability to efficiently load and deliver anticancer drugs. Covalent organic frameworks (COF)-based nanocarriers (CONs) have exhibited great p...

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Bibliographic Details
Main Authors: Chaoyu Wang, Huiming Liu, Shuai Liu, Zhijun Wang, Jianhua Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Chemistry
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2020.00488/full