Regulator of G-protein signaling 18 controls both platelet generation and function.

Regulator of G-protein signaling 18 controls both platelet generation and function.

RGS18 is a myeloerythroid lineage-specific regulator of G-protein signaling, highly expressed in megakaryocytes (MKs) and platelets. In the present study, we describe the first generation of a RGS18 knockout mouse model (RGS18-/-). Interesting phenotypic differences between RGS18-/- and wild-type (W...

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Bibliographic Details
Main Authors: Nathalie Delesque-Touchard, Caroline Pendaries, Cécile Volle-Challier, Laurence Millet, Véronique Salel, Caroline Hervé, Anne-Marie Pflieger, Laurence Berthou-Soulie, Catherine Prades, Tania Sorg, Jean-Marc Herbert, Pierre Savi, Françoise Bono
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4236145?pdf=render

Internet

http://europepmc.org/articles/PMC4236145?pdf=render

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