TSPO and amyloid deposits in sub-regions of the hippocampus in the 3xTgAD mouse model of Alzheimer’s disease

TSPO and amyloid deposits in sub-regions of the hippocampus in the 3xTgAD mouse model of Alzheimer’s disease

The involvement of the 18kDa translocator protein (TSPO), a marker of neuroinflammation, in Alzheimer's disease (AD) remains controversial. In the present report, we used [125I]-CLINDE, a SPECT TSPO radiotracer never before used in AD, and we investigated the relationship between TSPO and amylo...

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Bibliographic Details
Main Authors: Benjamin B. Tournier, Stergios Tsartsalis, Daphney Rigaud, Christine Fossey, Thomas Cailly, Frédéric Fabis, Tien Pham, Marie-Claude Grégoire, Eniko Kövari, Marcelle Moulin-Sallanon, Armand Savioz, Philippe Millet
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Neurobiology of Disease
Subjects:
Neuroinflammation
Alzheimer’s disease
TSPO
CLINDE
DRM106
3xTgAD
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996118306223

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http://www.sciencedirect.com/science/article/pii/S0969996118306223

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