Aqueous fraction of Beta vulgaris ameliorates hyperglycemia in diabetic mice due to enhanced glucose stimulated insulin secretion, mediated by acetylcholine and GLP-1, and elevated glucose uptake via increased membrane bound GLUT4 transporters.

Aqueous fraction of Beta vulgaris ameliorates hyperglycemia in diabetic mice due to enhanced glucose stimulated insulin secretion, mediated by acetylcholine and GLP-1, and elevated glucose uptake via increased membrane bound GLUT4 transporters.

<h4>Background</h4>The study was designed to investigate the probable mechanisms of anti-hyperglycemic activity of B. Vulgaris.<h4>Methodology/principal findings</h4>Aqueous fraction of B. Vulgaris extract was the only active fraction (50mg/kg). Plasma insulin level was found...

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Bibliographic Details
Main Authors: Ashraf Ul Kabir, Mehdi Bin Samad, Arif Ahmed, Mohammad Rajib Jahan, Farjana Akhter, Jinat Tasnim, S M Nageeb Hasan, Sania Sarker Sayfe, J M A Hannan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0116546

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https://doi.org/10.1371/journal.pone.0116546

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