Aqueous fraction of Beta vulgaris ameliorates hyperglycemia in diabetic mice due to enhanced glucose stimulated insulin secretion, mediated by acetylcholine and GLP-1, and elevated glucose uptake via increased membrane bound GLUT4 transporters.
<h4>Background</h4>The study was designed to investigate the probable mechanisms of anti-hyperglycemic activity of B. Vulgaris.<h4>Methodology/principal findings</h4>Aqueous fraction of B. Vulgaris extract was the only active fraction (50mg/kg). Plasma insulin level was found...
Main Authors: | Ashraf Ul Kabir, Mehdi Bin Samad, Arif Ahmed, Mohammad Rajib Jahan, Farjana Akhter, Jinat Tasnim, S M Nageeb Hasan, Sania Sarker Sayfe, J M A Hannan |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0116546 |
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