Combination of suberoylanilide hydroxamic acid with heavy ion therapy shows promising effects in infantile sarcoma cell lines

Combination of suberoylanilide hydroxamic acid with heavy ion therapy shows promising effects in infantile sarcoma cell lines

<p>Abstract</p> <p>Introduction</p> <p>The pan-HDAC inhibitor (HDACI) suberoylanilide hydroxamic acid (SAHA) has previously shown to be a radio-sensitizer to conventional photon radiotherapy (XRT) in pediatric sarcoma cell lines. Here, we investigate its effect on the r...

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Bibliographic Details
Main Authors: Kulozik Andreas E, Bischof Marc, Brons Stephan, Perez Ramon, Huber Peter E, Weber Klaus-J, Richter Karsten, Thiemann Markus, Oertel Susanne, Ehemann Volker, Debus Jürgen, Blattmann Claudia
Format: Article
Language:English
Published: BMC 2011-09-01
Series:Radiation Oncology
Subjects:
Infantile sarcoma
histone deacetylase inhibition
heavy ion radiotherapy
suberoylanilide hydroxamic acid
SAHA
Online Access:http://www.ro-journal.com/content/6/1/119

Internet

http://www.ro-journal.com/content/6/1/119

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