Type I interferon receptor knockout mice as models for infection of highly pathogenic viruses with outbreak potential

Type I interferon receptor knockout mice as models for infection of highly pathogenic viruses with outbreak potential

Due to their inability to generate a complete immune response, mice knockout for type I interferon (IFN) receptors (Ifnar–/–) are more susceptible to viral infections, and are thus commonly used for pathogenesis studies. This mouse model has been used to study many diseases caused by highly pathogen...

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Bibliographic Details
Main Authors: Gary Wong, Xiang-Guo Qiu
Format: Article
Language:English
Published: Science Press, PR China 2018-01-01
Series:Zoological Research
Subjects:
Ifnar
Mice
Animal model
Flavivirus
Filovirus
Arenavirus
Bunyavirus
Henipavirus
Online Access:http://www.zoores.ac.cn/EN/abstract/abstract3835.shtml

Internet

http://www.zoores.ac.cn/EN/abstract/abstract3835.shtml

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