Na+/Ca2 + Exchange and Pacemaker Activity of Interstitial Cells of Cajal

Na+/Ca2 + Exchange and Pacemaker Activity of Interstitial Cells of Cajal

Interstitial cells of Cajal (ICC) are pacemaker cells that generate electrical slow waves in gastrointestinal (GI) smooth muscles. Slow waves organize basic motor patterns, such as peristalsis and segmentation in the GI tract. Slow waves depend upon activation of Ca2+-activated Cl– channels (CaCC) e...

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Bibliographic Details
Main Authors: Haifeng Zheng, Bernard T. Drumm, Mei Hong Zhu, Yeming Xie, Kate E. O’Driscoll, Salah A. Baker, Brian A. Perrino, Sang Don Koh, Kenton M. Sanders
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Physiology
Subjects:
ANO1
Ca2+-activated Cl– current
slow waves
smooth muscle
gastrointestinal motility
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00230/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2020.00230/full

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