Selective pharmacological modulation of pyramidal neurons and interneurons in the CA1 region of the rat hippocampus

The hippocampus is a complex network tightly regulated by interactions between excitatory and inhibitory neurons. In neurodegenerative disorders where cognitive functions such as learning and memory are impaired this excitation-inhibition balance may be altered. Interestingly, the uncompetitive NMDA...

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Bibliographic Details
Main Authors: Marzia eMartina, Tanya eComas, Geoff A.R. Mealing
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-03-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2013.00024/full