Effects of repeated adolescent stress and serotonin transporter gene partial knockout in mice on behaviors and brain structures relevant to major depression

Effects of repeated adolescent stress and serotonin transporter gene partial knockout in mice on behaviors and brain structures relevant to major depression

In humans, exposure to stress during development is associated with structural and functional alterations of the prefrontal cortex (PFC), amygdala (AMY), and hippocampus (HC) and their circuits of connectivity, and with an increased risk for developing major depressive disorder particularly in carri...

Full description

Bibliographic Details
Main Authors: Simona eSpinelli, Tanja eMueller, Miriam eFriedel, Hannes eSigrist, Mark R Henkelman, Markus eRudin, Erich eSeifritz, Christopher R Pryce
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Magnetic Resonance Imaging
serotonin transporter gene
mouse model
major depression
development.
adolescent stress
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2013.00215/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2013.00215/full

Similar Items