Coronin-1A links cytoskeleton dynamics to TCR alpha beta-induced cell signaling.

Coronin-1A links cytoskeleton dynamics to TCR alpha beta-induced cell signaling.

Actin polymerization plays a critical role in activated T lymphocytes both in regulating T cell receptor (TCR)-induced immunological synapse (IS) formation and signaling. Using gene targeting, we demonstrate that the hematopoietic specific, actin- and Arp2/3 complex-binding protein coronin-1A contri...

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Bibliographic Details
Main Authors: Bénédicte Mugnier, Béatrice Nal, Christophe Verthuy, Claude Boyer, David Lam, Lionel Chasson, Vincent Nieoullon, Geneviève Chazal, Xiao-Jun Guo, Hai-Tao He, Dominique Rueff-Juy, Andrés Alcover, Pierre Ferrier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2568942?pdf=render

Internet

http://europepmc.org/articles/PMC2568942?pdf=render

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