Coronin-1A links cytoskeleton dynamics to TCR alpha beta-induced cell signaling.
Actin polymerization plays a critical role in activated T lymphocytes both in regulating T cell receptor (TCR)-induced immunological synapse (IS) formation and signaling. Using gene targeting, we demonstrate that the hematopoietic specific, actin- and Arp2/3 complex-binding protein coronin-1A contri...
Main Authors: | Bénédicte Mugnier, Béatrice Nal, Christophe Verthuy, Claude Boyer, David Lam, Lionel Chasson, Vincent Nieoullon, Geneviève Chazal, Xiao-Jun Guo, Hai-Tao He, Dominique Rueff-Juy, Andrés Alcover, Pierre Ferrier |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2568942?pdf=render |
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