From quiescence to proliferation : Cdk oscillations drive the mammalian cell cycle

From quiescence to proliferation : Cdk oscillations drive the mammalian cell cycle

We recently proposed a detailed model describing the dynamics of the network of cyclin-dependent kinases (Cdks) driving the mammalian cell cycle [Gérard, C. and Goldbeter, A. (2009). Temporal self-organization of the cyclin/Cdk network driving the mammalian cell cycle. Proc. Natl. Acad. Sci...

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Bibliographic Details
Main Authors: Claude eGérard, Albert eGoldbeter
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-11-01
Series:Frontiers in Physiology
Subjects:
Cell Proliferation
computational model
Mammalian cell cycle
Cdk oscillations
Limit cycle oscillations
Cellular quiescence
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00413/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00413/full

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