Structural insight into mutations at 155 position of valosin containing protein (VCP) linked to inclusion body myopathy with Paget disease of bone and frontotemporal Dementia

Structural insight into mutations at 155 position of valosin containing protein (VCP) linked to inclusion body myopathy with Paget disease of bone and frontotemporal Dementia

Mutations in Valosin-containing protein (VCP) have been implicated in the pathology linked to inclusion body myopathy, paget disease of bone and frontotemporal dementia (IBMPFD). VCP is an essential component of AAA-ATPase superfamily involved in various cellular functions. Advanced In-silico analys...

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Bibliographic Details
Main Authors: Rui Wu, Zhijie Wei, Li Zhang
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Saudi Journal of Biological Sciences
Subjects:
Valosin-containing protein
Myopathy
Paget disease
Dementia
Molecular docking
Online Access:http://www.sciencedirect.com/science/article/pii/S1319562X21001212

Internet

http://www.sciencedirect.com/science/article/pii/S1319562X21001212

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