Genome-wide RNAi screening identifies genes inhibiting the migration of glioblastoma cells.

Glioblastoma Multiforme (GBM) cells are highly invasive, infiltrating into the surrounding normal brain tissue, making it impossible to completely eradicate GBM tumors by surgery or radiation. Increasing evidence also shows that these migratory cells are highly resistant to cytotoxic reagents, but d...

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Bibliographic Details
Main Authors: Jian Yang, Jing Fan, Ying Li, Fuhai Li, Peikai Chen, Yubo Fan, Xiaofeng Xia, Stephen T Wong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3625150?pdf=render