Why Is COVID-19 More Severe in Patients With Diabetes? The Role of Angiotensin-Converting Enzyme 2, Endothelial Dysfunction and the Immunoinflammatory System

Why Is COVID-19 More Severe in Patients With Diabetes? The Role of Angiotensin-Converting Enzyme 2, Endothelial Dysfunction and the Immunoinflammatory System

Meta-analyses have indicated that individuals with type 1 or type 2 diabetes are at increased risk of suffering a severe form of COVID-19 and have a higher mortality rate than the non-diabetic population. Patients with diabetes have chronic, low-level systemic inflammation, which results in global c...

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Bibliographic Details
Main Authors: Jacob Roberts, Antonia L. Pritchard, Andrew T. Treweeke, Adriano G. Rossi, Nicole Brace, Paul Cahill, Sandra M. MacRury, Jun Wei, Ian L. Megson
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
COVID-19
SARS– CoV– 2
diabetes
endothelium
oxidative stress
angiotensin converting enzyme-2
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2020.629933/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2020.629933/full

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