Characterization of humoral immune responses and degree of protection induced by influenza vaccine in cotton rats: Effects of low vaccine dose and single vs booster vaccination

Abstract Introduction Cotton rats are a suitable model for the study of influenza disease symptoms and responses to influenza vaccination. We have previously shown that two immunizations with 15 µg whole inactivated virus (WIV) influenza vaccine could completely protect animals from infection with t...

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Bibliographic Details
Main Authors: Yoshita Bhide, Wei Dong, Tjarko Meijerhof, Jacqueline deVries‐Idema, Hubert G. Niesters, Anke Huckriede
Format: Article
Language:English
Published: Wiley 2020-09-01
Series:Immunity, Inflammation and Disease
Subjects:
Online Access:https://doi.org/10.1002/iid3.303