FAIM2 Promotes Non-Small Cell Lung Cancer Cell Growth and Bone Metastasis by Activating the Wnt/β-Catenin Pathway

FAIM2 Promotes Non-Small Cell Lung Cancer Cell Growth and Bone Metastasis by Activating the Wnt/β-Catenin Pathway

AimBone metastasis is the major reason for the poor prognosis and high mortality rate of non-small cell lung cancer (NSCLC) patients. This study explored the function and underlying mechanism of Fas apoptotic inhibitory molecule 2 (FAIM2) in the bone metastasis of NSCLC.MethodsSamples of normal lung...

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Bibliographic Details
Main Authors: Kelin She, Wensheng Yang, Mengna Li, Wei Xiong, Ming Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Oncology
Subjects:
NSCLC
FAIM2
bone metastasis
Wnt pathway
EMT
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.690142/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.690142/full

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