Functional roles of protein splicing factors

RNA splicing is one of the fundamental processes in gene expression in eukaryotes. Splicing of pre-mRNA is catalysed by a large ribonucleoprotein complex called the spliceosome, which consists of five small nuclear RNAs and numerous protein factors. The spliceosome is a highly dynamic structure, ass...

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Bibliographic Details
Main Authors: Hsin‑Chou Chen, Soo‑Chen Cheng
Format: Article
Language:English
Published: Portland Press, Biochemical Society 2012-04-01
Series:Bioscience Reports
Subjects:
Online Access:http://www.bioscirep.org/bsr/032/0345/bsr0320345.htm