Effect of Hyperglycemia on Gene Expression during Early Organogenesis in Mice.

Effect of Hyperglycemia on Gene Expression during Early Organogenesis in Mice.

Cardiovascular and neural malformations are common sequels of diabetic pregnancies, but the underlying molecular mechanisms remain unknown. We hypothesized that maternal hyperglycemia would affect the embryos most shortly after the glucose-sensitive time window at embryonic day (ED) 7.5 in mice.Mice...

Full description

Bibliographic Details
Main Authors: Jing Zhao, Theodorus B M Hakvoort, A Marcel Willemsen, Aldo Jongejan, Milka Sokolovic, Edward J Bradley, Vincent C J de Boer, Frank Baas, Antoine H C van Kampen, Wouter H Lamers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4951019?pdf=render

Internet

http://europepmc.org/articles/PMC4951019?pdf=render

Similar Items