Comparison of Germline versus Somatic BAP1 Mutations for Risk of Metastasis in Uveal Melanoma

Comparison of Germline versus Somatic BAP1 Mutations for Risk of Metastasis in Uveal Melanoma

Abstract Background Germline mutations in BAP1 have been associated with BAP1-Tumor Predisposition Syndrome (BAP1-TPDS), a predisposition to multiple tumors within a family that includes uveal melanoma (UM), cutaneous melanoma, malignant mesothelioma and renal cell carcinoma. Alternatively, somatic...

Full description

Bibliographic Details
Main Authors: K. G. Ewens, E. Lalonde, J. Richards-Yutz, C. L. Shields, A. Ganguly
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Cancer
Subjects:
uveal melanoma
ocular/eye cancer
BAP1
germline mutations
somatic mutations
Online Access:http://link.springer.com/article/10.1186/s12885-018-5079-x

Internet

http://link.springer.com/article/10.1186/s12885-018-5079-x

Similar Items