Sex-specific differences in organic anion transporting polypeptide 1a4 (Oatp1a4) functional expression at the blood–brain barrier in Sprague–Dawley rats
Abstract Background Targeting endogenous blood–brain barrier (BBB) transporters such as organic anion transporting polypeptide 1a4 (Oatp1a4) can facilitate drug delivery for treatment of neurological diseases. Advancement of Oatp targeting for optimization of CNS drug delivery requires characterizat...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-09-01
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Series: | Fluids and Barriers of the CNS |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12987-018-0110-9 |