Design Space Approach in Optimization of Fluid Bed Granulation and Tablets Compression Process

The aim of this study was to optimize fluid bed granulation and tablets compression processes using design space approach. Type of diluent, binder concentration, temperature during mixing, granulation and drying, spray rate, and atomization pressure were recognized as critical formulation and proces...

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Bibliographic Details
Main Authors: Jelena Djuriš, Djordje Medarević, Marko Krstić, Ivana Vasiljević, Ivana Mašić, Svetlana Ibrić
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/2012/185085