Fob1 and Fob2 Proteins Are Virulence Determinants of Rhizopus oryzae via Facilitating Iron Uptake from Ferrioxamine.

Dialysis patients with chronic renal failure receiving deferoxamine for treating iron overload are uniquely predisposed for mucormycosis, which is most often caused by Rhizopus oryzae. Although the deferoxamine siderophore is not secreted by Mucorales, previous studies established that Rhizopus spec...

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Bibliographic Details
Main Authors: Mingfu Liu, Lin Lin, Teclegiorgis Gebremariam, Guanpingsheng Luo, Christopher D Skory, Samuel W French, Tsui-Fen Chou, John E Edwards, Ashraf S Ibrahim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-05-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4431732?pdf=render