The ATF6-EGF Pathway Mediates the Awakening of Slow-Cycling Chemoresistant Cells and Tumor Recurrence by Stimulating Tumor Angiogenesis

The ATF6-EGF Pathway Mediates the Awakening of Slow-Cycling Chemoresistant Cells and Tumor Recurrence by Stimulating Tumor Angiogenesis

Slow-cycling cancer cells (SCCs) with a quiescence-like phenotype are believed to perpetrate cancer relapse and progression. However, the mechanisms that mediate SCC-derived tumor recurrence are poorly understood. Here, we investigated the mechanisms underlying cancer recurrence after chemotherapy,...

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Bibliographic Details
Main Authors: Jaebeom Cho, Hye-Young Min, Honglan Pei, Xuan Wei, Jeong Yeon Sim, Shin-Hyung Park, Su Jung Hwang, Hyo-Jong Lee, Sungyoul Hong, Young Kee Shin, Ho-Young Lee
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cancers
Subjects:
slow-cycling cancer cells
chemoresistance
angiogenesis
tumor recurrence
Online Access:https://www.mdpi.com/2072-6694/12/7/1772

Internet

https://www.mdpi.com/2072-6694/12/7/1772

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