Nanodomain coupling explains Ca2+ independence of transmitter release time course at a fast central synapse
A puzzling property of synaptic transmission, originally established at the neuromuscular junction, is that the time course of transmitter release is independent of the extracellular Ca2+ concentration ([Ca2+]o), whereas the rate of release is highly [Ca2+]o-dependent. Here, we examine the time cour...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2014-12-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/04057 |