Deletion of MicroRNA-144/451 Cluster Aggravated Brain Injury in Intracerebral Hemorrhage Mice by Targeting 14-3-3ζ

Deletion of MicroRNA-144/451 Cluster Aggravated Brain Injury in Intracerebral Hemorrhage Mice by Targeting 14-3-3ζ

This study aims at evaluating the importance and its underlying mechanism of the cluster of microRNA-144/451 (miR-144/451) in the models with intracerebral hemorrhage (ICH). A model of collagenase-induced mice with ICH and a model of mice with simple miR-144/451 gene knockout (KO) were used in this...

Full description

Bibliographic Details
Main Authors: Xiaohong Wang, Yin Hong, Lei Wu, Xiaochun Duan, Yue Hu, Yongan Sun, Yanqiu Wei, Zhen Dong, Chenghao Wu, Duonan Yu, Jun Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Neurology
Subjects:
microRNA-451
intracerebral hemorrhage (ICH)
inflammation
14-3-3ζ
mice
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2020.551411/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2020.551411/full

Similar Items