Mathematical modeling of bacterial kinetics to predict the impact of antibiotic colonic exposure and treatment duration on the amount of resistant enterobacteria excreted.

Fecal excretion of antibiotics and resistant bacteria in the environment are major public health threats associated with extensive farming and modern medical care. Innovative strategies that can reduce the intestinal antibiotic concentrations during treatments are in development. However, the effect...

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Bibliographic Details
Main Authors: Thu Thuy Nguyen, Jeremie Guedj, Elisabeth Chachaty, Jean de Gunzburg, Antoine Andremont, France Mentré
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-09-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4161292?pdf=render