O-GlcNAcylation and its role in the immune system

Abstract O-linked-N-acetylglucosaminylation (O-GlcNAcylation) is a type of glycosylation that occurs when a monosaccharide, O-GlcNAc, is added onto serine or threonine residues of nuclear or cytoplasmic proteins by O-GlcNAc transferase (OGT) and which can be reversibly removed by O-GlcNAcase (OGA)....

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Bibliographic Details
Main Authors: Yi-Hsuan Chang, Chia-Lin Weng, Kuo-I Lin
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Journal of Biomedical Science
Subjects:
OGT
OGA
Online Access:http://link.springer.com/article/10.1186/s12929-020-00648-9