Phenotypical Characterization of Spleen Remodeling in Murine Experimental Visceral Leishmaniasis

Phenotypical Characterization of Spleen Remodeling in Murine Experimental Visceral Leishmaniasis

Background: Visceral leishmaniasis (VL) is caused by Leishmania infantum or L. donovani infection. One of the main problems related to this disease is the emergence of severe clinical forms with a lethality of 5–20%, even while under specific treatment. In humans and other species susceptible to fat...

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Main Authors: Caroline Vilas Boas de Melo, Micely D'El-Rei Hermida, Bianca R. Mesquita, Jonathan L. M. Fontes, Jasper J. Koning, Manuela da Silva Solcà, Bruno B. Benevides, Girlândia B. S. Mota, Luiz A. R. Freitas, Reina E. Mebius, Washington L. C. dos-Santos
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Immunology
Subjects:
visceral leishmaniasis
white pulp remodeling
spleen disorganization
lymphoid tissue inducer cells
spleen pathology
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00653/full

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https://www.frontiersin.org/article/10.3389/fimmu.2020.00653/full

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