Aromatase gene polymorphisms are associated with survival among patients with cardiovascular disease in a sex-specific manner.

Aromatase gene polymorphisms are associated with survival among patients with cardiovascular disease in a sex-specific manner.

CYP19A1 encodes aromatase, the enzyme responsible for the conversion of androgens to estrogens, and may play a role in variation in outcomes among men and women with cardiovascular disease. We sought to examine genetic variation in CYP19A1 for its potential role in sex differences in cardiovascular...

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Bibliographic Details
Main Authors: Amber L Beitelshees, Julie A Johnson, Megan L Hames, Yan Gong, Rhonda M Cooper-Dehoff, Jun Wu, Sharon Cresci, Cynthia X Ma, Carl J Pepine, Michael A Province, John A Spertus, Howard L McLeod
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3000815?pdf=render

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http://europepmc.org/articles/PMC3000815?pdf=render

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