Role of Human Leukocyte Antigen System as A Predictive Biomarker for Checkpoint-Based Immunotherapy in Cancer Patients

Role of Human Leukocyte Antigen System as A Predictive Biomarker for Checkpoint-Based Immunotherapy in Cancer Patients

<b> </b>Recent advances in cancer immunotherapy have clearly shown that checkpoint-based immunotherapy is effective in a small subgroup of cancer patients. However, no effective predictive biomarker has been identified so far. The major histocompatibility complex, better known in humans...

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Bibliographic Details
Main Authors: Francesco Sabbatino, Luigi Liguori, Giovanna Polcaro, Ilaria Salvato, Gaetano Caramori, Francesco A. Salzano, Vincenzo Casolaro, Cristiana Stellato, Jessica Dal Col, Stefano Pepe
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
major histocompatibility complex (MHC), human leukocyte antigen (HLA), antigen processing machinery (APM) molecules
carcinogenesis
tumor predisposition
biomarker
cancer immunotherapy
Online Access:https://www.mdpi.com/1422-0067/21/19/7295

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https://www.mdpi.com/1422-0067/21/19/7295

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