Essential role of domain III of nonstructural protein 5A for hepatitis C virus infectious particle assembly.

Essential role of domain III of nonstructural protein 5A for hepatitis C virus infectious particle assembly.

Persistent infection with the hepatitis C virus (HCV) is a major risk factor for the development of liver cirrhosis and hepatocellular carcinoma. With an estimated about 3% of the world population infected with this virus, the lack of a prophylactic vaccine and a selective therapy, chronic hepatitis...

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Bibliographic Details
Main Authors: Nicole Appel, Margarita Zayas, Sven Miller, Jacomine Krijnse-Locker, Torsten Schaller, Peter Friebe, Stephanie Kallis, Ulrike Engel, Ralf Bartenschlager
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-03-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2268006?pdf=render

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http://europepmc.org/articles/PMC2268006?pdf=render

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