PDGFRα: Expression and Function during Mitral Valve Morphogenesis

PDGFRα: Expression and Function during Mitral Valve Morphogenesis

Mitral valve prolapse (MVP) is a common form of valve disease and can lead to serious secondary complications. The recent identification of MVP causal mutations in primary cilia-related genes has prompted the investigation of cilia-mediated mechanisms of disease inception. Here, we investigate the r...

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Bibliographic Details
Main Authors: Kelsey Moore, Diana Fulmer, Lilong Guo, Natalie Koren, Janiece Glover, Reece Moore, Cortney Gensemer, Tyler Beck, Jordan Morningstar, Rebecca Stairley, Russell A. Norris
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
PDGFRα
mitral valve
endothelial
ERK1/2
cardiac development
Online Access:https://www.mdpi.com/2308-3425/8/3/28

Internet

https://www.mdpi.com/2308-3425/8/3/28

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