Emerging Place of JAK Inhibitors in the Treatment of Inborn Errors of Immunity

Among inborn errors of immunity (IEIs), some conditions are characterized by inflammation and autoimmunity at the front line and are particularly challenging to treat. Monogenic diseases associated with gain-of-function mutations in genes critical for cytokine signaling through the JAK-STAT pathway...

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Bibliographic Details
Main Authors: Jérôme Hadjadj, Marie-Louise Frémond, Bénédicte Neven
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.717388/full