Stroke aetiological classification reliability and effect on trial sample size: systematic review, meta-analysis and statistical modelling

Stroke aetiological classification reliability and effect on trial sample size: systematic review, meta-analysis and statistical modelling

Abstract Background Inter-observer variability in stroke aetiological classification may have an effect on trial power and estimation of treatment effect. We modelled the effect of misclassification on required sample size in a hypothetical cardioembolic (CE) stroke trial. Methods We performed a sys...

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Bibliographic Details
Main Authors: Azmil H. Abdul-Rahim, David Alexander Dickie, Johann R. Selvarajah, Kennedy R. Lees, Terence J. Quinn, On behalf of VISTA Collaborators
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Trials
Subjects:
Stroke
Classification
Aetiology
Online Access:http://link.springer.com/article/10.1186/s13063-019-3222-x

Internet

http://link.springer.com/article/10.1186/s13063-019-3222-x

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