Manipulation therapy prior to diagnosis induced primary osteosarcoma metastasis--from clinical to basic research.

Manipulation therapy prior to diagnosis induced primary osteosarcoma metastasis--from clinical to basic research.

Osteosarcoma (OS) patients who suffer manipulation therapy (MT) prior to diagnosis resulted in poor prognosis with increasing metastasis or recurrence rate. The aim of the study is to establish an in vivo model to identify the effects of MT on OS. The enrolled 235 OS patients were followed up in thi...

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Bibliographic Details
Main Authors: Jir-You Wang, Po-Kuei Wu, Paul Chih-Hsueh Chen, Chuen-Chuan Yen, Giun-Yi Hung, Cheng-Fong Chen, Shih-Chieh Hung, Shih-Fen Tsai, Chien-Lin Liu, Tain-Hsiung Chen, Wei-Ming Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4013034?pdf=render

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http://europepmc.org/articles/PMC4013034?pdf=render

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