Whole-genome plasma sequencing reveals focal amplifications as a driving force in metastatic prostate cancer

Whole-genome plasma sequencing reveals focal amplifications as a driving force in metastatic prostate cancer

The genomic features of metastatic prostate cancer are beginning to be understood. Here, the authors performed whole genome sequencing of plasma samples from these patients and found a high plasticity of the cancer genomes with newly occurring focal amplifications as a driving force in progression.

Bibliographic Details
Main Authors: Peter Ulz, Jelena Belic, Ricarda Graf, Martina Auer, Ingrid Lafer, Katja Fischereder, Gerald Webersinke, Karl Pummer, Herbert Augustin, Martin Pichler, Gerald Hoefler, Thomas Bauernhofer, Jochen B. Geigl, Ellen Heitzer, Michael R. Speicher
Format: Article
Language:English
Published: Nature Publishing Group 2016-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12008

Internet

https://doi.org/10.1038/ncomms12008

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