Typing complex meningococcal vaccines to understand diversity and population structure of key vaccine antigens [version 2; peer review: 2 approved]

Background: Protein-conjugate capsular polysaccharide vaccines can potentially control invasive meningococcal disease (IMD) caused by five (A, C, W, X, Y) of the six IMD-associated serogroups.  Concerns raised by immunological similarity of the serogroup B capsule to human neural cell carbohydrates,...

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Bibliographic Details
Main Authors: Charlene M. C. Rodrigues, Hannah Chan, Caroline Vipond, Keith Jolley, Odile B. Harrison, Jun Wheeler, Gail Whiting, Ian M. Feavers, Martin C. J. Maiden
Format: Article
Language:English
Published: Wellcome 2019-03-01
Series:Wellcome Open Research
Online Access:https://wellcomeopenresearch.org/articles/3-151/v2