Targeting Beta-Blocker Drug–Drug Interactions with Fibrinogen Blood Plasma Protein: A Computational and Experimental Study

In this work, one of the most prevalent polypharmacology drug–drug interaction events that occurs between two widely used beta-blocker drugs—i.e., acebutolol and propranolol—with the most abundant blood plasma fibrinogen protein was evaluated. Towards that end, molecular docking and Density Function...

Full description

Bibliographic Details
Main Authors: Michael González-Durruthy, Riccardo Concu, Laura F. Osmari Vendrame, Ivana Zanella, Juan M. Ruso, M. Natália D.S. Cordeiro
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Molecules
Subjects:
DFT
Online Access:https://www.mdpi.com/1420-3049/25/22/5425