In Silico Study, Physicochemical, and In Vitro Lipase Inhibitory Activity of <i>α</i>,<i>β</i>-Amyrenone Inclusion Complexes with Cyclodextrins

In Silico Study, Physicochemical, and In Vitro Lipase Inhibitory Activity of <i>α</i>,<i>β</i>-Amyrenone Inclusion Complexes with Cyclodextrins

<i>α</i>,<i>β</i>-amyrenone (ABAME) is a triterpene derivative with many biological activities; however, its potential pharmacological use is hindered by its low solubility in water. In this context, the present work aimed to develop inclusion complexes (ICs) of ABAME with &l...

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Bibliographic Details
Main Authors: Luana Carvalho de Oliveira, Danielle Lima Bezerra de Menezes, Valéria Costa da Silva, Estela Mariana Guimarães Lourenço, Paulo Henrique Santana Miranda, Márcia de Jesus Amazonas da Silva, Emerson Silva Lima, Valdir Florêncio da Veiga Júnior, Ricardo Neves Marreto, Attilio Converti, Euzébio Guimaraes Barbosa, Ádley Antonini Neves de Lima
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
amyrenone
triterpenes
cyclodextrins
inclusion complexes
lipase activity
Online Access:https://www.mdpi.com/1422-0067/22/18/9882

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https://www.mdpi.com/1422-0067/22/18/9882

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