Subcellular localization and distribution of the reduced folate carrier in normal rat tissues

The reduced folate carrier (Rfc1; Slc19a1) mediated transport of reduced folates and antifolate drugs such as methotrexate (MTX) play an essential role in physiological folate homeostasis and MTX cancer chemotherapy. As no systematic reports are as yet available correlating Rfc1 gene expression and...

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Bibliographic Details
Main Authors: M. Hinken, S. Halwachs, C. Kneuer, W. Honscha
Format: Article
Language:English
Published: PAGEPress Publications 2011-01-01
Series:European Journal of Histochemistry
Subjects:
Online Access:http://www.ejh.it/index.php/ejh/article/view/1797