Subcellular localization and distribution of the reduced folate carrier in normal rat tissues
The reduced folate carrier (Rfc1; Slc19a1) mediated transport of reduced folates and antifolate drugs such as methotrexate (MTX) play an essential role in physiological folate homeostasis and MTX cancer chemotherapy. As no systematic reports are as yet available correlating Rfc1 gene expression and...
Main Authors: | M. Hinken, S. Halwachs, C. Kneuer, W. Honscha |
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Format: | Article |
Language: | English |
Published: |
PAGEPress Publications
2011-01-01
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Series: | European Journal of Histochemistry |
Subjects: | |
Online Access: | http://www.ejh.it/index.php/ejh/article/view/1797 |
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