Laminar and cellular analyses of reduced somatostatin gene expression in the subgenual anterior cingulate cortex in major depression

Somatostatin (SST), a neuropeptide expressed in dendritic-targeting gamma-aminobutyric acid (GABA) neurons, is decreased across corticolimbic areas in major depressive disorder (MDD). SST-positive GABA neurons form heterogeneous subgroups with different laminar distributions and electrophysiological...

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Bibliographic Details
Main Authors: Marianne L. Seney, Adam Tripp, Samuel McCune, David A. Lewis, Etienne Sibille
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996114002988