Intracellular Events and Cell Fate in Filovirus Infection

Intracellular Events and Cell Fate in Filovirus Infection

Marburg and Ebola viruses cause a severe hemorrhagic disease in humans with high fatality rates. Early target cells of filoviruses are monocytes, macrophages, and dendritic cells. The infection spreads to the liver, spleen and later other organs by blood and lymph flow. A hallmark of filovirus infec...

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Bibliographic Details
Main Authors: Elena Ryabchikova, Ronald B. Corley, Elke Mühlberger, Judith Olejnik
Format: Article
Language:English
Published: MDPI AG 2011-08-01
Series:Viruses
Subjects:
Ebola Virus
Marburg Virus
filoviruses
viral replication cycle
target cells
animal models
ultrastructural analysis
virus-cell interaction
bystander apoptosis
cell death
Online Access:http://www.mdpi.com/1999-4915/3/8/1501/

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http://www.mdpi.com/1999-4915/3/8/1501/

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